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Index – Tech-Science – America hit the fourth wave

In the United States, after a temporary decline, the number of coronavirus infections rose sharply again. At first, they seemed to be just isolated focal points. In Orlando, Florida, recently reopened and tempting with huge discounts Disney world In his city, for example, the number of cases increased tenfold. However, it is now clear that the entire country has been affected, with a gradual increase in the number of people infected, hospitalized and dying from the disease in all 50 US states. As a result, several places, such as Los Angeles County again restrictive Measures were introduced by the authorities.

The background to this phenomenon appears to be controversial at first, as the United States was one of the first to initiate vaccinations, and has been at the forefront of the world in terms of vaccination rates since its inception. It should be noted here that although the United States, for example, was ahead of Britain in terms of the proportion of vaccines administered to the population, there was an earlier and even greater increase in the initially incomprehensible increase in the number of cases. However, the island nation used different tactics and, in part, other vaccinations. In the United Kingdom, a large proportion of those vaccinated received the partially developed AstraZeneca vaccine, while this is not available at all in the United States.

Another fundamental difference is that England and its neighbors, in contrast to the prescribing information for vaccines, have sought to get as many people as possible to receive at least one vaccine rather than receiving fewer than the two prescribed doses. There was also some logic to this, as the first data indicated that Pfizer’s vaccine, for example, produced significant protection even after a single dose, or rather, so to speak, against variants of the coronavirus that were then circulating. The Indian mutant, recently known as Delta, has arrived and is protected from current vaccines, but this requires a second or even a third dose. The two countries are similar in that the Indian variant emerged very early in both places and then quickly became dominant, most likely through the large number of Indian immigrants living and working in the United States and the United Kingdom.

There is no doubt that the Indian variant will become dominant in Hungary as well, it is only a matter of time. This was also the case for the British variant of the spring, and it is also likely that this will constantly come to us from this trend. So far, Hungary has followed manufacturers’ regulations and licensing authorities, and from the start it has been striving to administer both doses. This sometimes involved blocking some of the charge directed at the second dose, but it achieved the expected result. In Hungary, the notable proportion of vaccinates have had two. In this, then, the American situation distinguishes us more than the British.

Another similarity is the proportion of those vaccinated, which roughly amounts to about 50 percent in most member states of the United States and Hungary. There is a difference in the proportion and nature of the vaccines used. Here in Britain, as in the UK, the British-Swedish AstraZeneca vaccine has been used, but not only that. Hungary has also used the Russian Sputnik vaccine and Chinese Sinopharm, and relatively little is known about the protective effects of the latter two against Indian mutants.

So what can be done?

Of course, no one wants restrictive measures to come back to us like Los Angeles. In America, the authorities see the solution in the continued use of the first and second doses of vaccines, since 99 percent of new hospital cases and deaths affect unvaccinated people. Additionally, the current (and former) president’s health advisor, Dr. Fauci is. Although President Biden’s goal of 70 percent vaccination is not met by the July 4th Independence Day deadline, local and national authorities are not giving up. They also mentioned positive and negative motivations in their communications, the provision of free beer in addition to vaccinations, and the withdrawal of support for vaccinations due to the Covid epidemic.

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There is little disagreement between the US health government and manufacturers about this. Representatives of the former, such as Dr. Fauci argues that there is currently no scientific evidence of the need for this except for a few groups of narrow patients. On the other hand, manufacturers, notably Pfizer, consider a third dose necessary, if not in the form of the current release, but at least in an updated version, which may include information from analysis of newer mutants. The current Hungarian development, which is based on infectious viruses in Hungary, also occurs in this way. In Hungary, we are getting closer and closer to implementing the third dose, with different vaccines than the first two. In practice, this currently means that those who received the first two of, for example, AstraZeneca or Sputnik V, recommended Pfizer or Moderna as the third dose, etc. This approach is unknown in clinical immunology and has been used for years as a “heterogeneous batch”. So the logic is definitely in it.

The author specializes in allergy and clinical immunology, c. professor.

(Cover image: Patients wait for their first dose of the vaccine in America. Photo: Micah Green/Bloomberg/Getty Images)