Scientists at the Paris Institute of Vision have recreated a vision of a completely blind man with light-sensitive proteins produced in algae.
Optogenetic therapy has been used in the treatment of blind patients. Writes for BBC News. In men, retinitis pigmentosa, an inflammation of the retinoblastoma, was diagnosed forty years ago. The disease affects more than two million people around the world. Although complete blindness is rare, the man completely lost his eyesight two decades ago. However, after today’s treatment
Once again able to perceive light with one eye.
The method is based on proteins produced by the algae, a subfamily of rhodopsin that provides photosensitivity to the retina, which changes its behavior when exposed to light. Microbes use them to move towards light. The first step in treatment was gene therapy. The genetic instructions from the algae to form rhodopsin were “passed on” to the cells in the remaining deep layers of the retina in the back of the eye. When they are exposed to light, an electrical signal is sent to the brain. However, since it only responds to yellow light,
The patient wears special glasses,
Which transmits the real world image to the back of the eye at the appropriate wavelength. It took months for enough rhodopsin to accumulate in the eye and for the brain to learn a new language to restore sight. According to the results published in Nature Medicine, the patient knew that the treatment worked when walking down the street
Note that he can see the lines of the pedestrian crossing.
The man was now able to grab and count things on the table. Hungarian neurobiologist Ruska Boutond also participated in the research.
Photo: José Allan Sahl and Butond Rusca, Natural Medicine
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