A link between paracetamol intake during pregnancy and symptoms of attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in children was found in a study of more than 70,000 children based on six European cohort studies.
The research, published in the European Journal of Epidemiology, was led by the Institute for Global Health Research (ISGlobal) in Barcelona.
Altogether, the experts analyzed data from 73,881 children, information on exposure to paracetamol at fetal or postnatal age, and at least one symptom of autism spectrum disorder or attention deficit hyperactivity disorder. Depending on the group study, 14 to 56 percent of mothers took paracetamol during pregnancy – He writes for the science and education portal EurekAlert.com.
According to the research, children exposed to paracetamol before birth were 19 percent more likely to have symptoms of autism spectrum disorder and 21 percent more likely to have symptoms of ADHD than children who were not exposed to paracetamol.
Our results are consistent with previous research. We also noted that exposure to paracetamol affects boys and girls in the same way, almost without any difference. “ Said Silvia Alimani, lead author of the study, is a researcher at ISGlobal.
“Based on the evidence, we agree with previous recommendations that paracetamol should not be banned in children and pregnant women, but should only be used when it is truly necessary.” Added Jordi Sunyer, ISGlobal expert.
In developed countries, 46 to 56 percent of pregnant women take paracetamol at some point in their pregnancy, which is considered the most common antipyretic and safe analgesic for pregnant women and children. However, there is increasing evidence that the prenatal effects of paracetamol may be associated with impaired cognitive functioning, multiple behavioral problems, and symptoms of ASD and ADHD.
According to the study, exposure to paracetamol after birth in infancy was not associated with symptoms of autism spectrum disorder.
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